Doctors Do A Blood Transfusion For The Involvement Of Patients In Trials Of New Cancer Drugs – Part 3 of 3
Another layer to the issue that should be examined is how proper the “exclusion criteria” regarding participation in clinical trials are in the first place. The exclusion factors take into account a drug’s toxicity and who is likely to be helped. “Exclusion criteria” are meant to care for patients by keeping people out who are too ill to metabolize a drug effectively, or too fragile to handle its side effects.
But drug companies want positive results so there can be pressure to select healthier patients to induce the drug look better. If doctors are bypassing the exclusion criteria, it may be that they believe the criteria are unfairly leaving some very sick patients out of trials who could benefit. “We have to make trusty exclusions are not selecting for the best patients that will make the drug look its best”.