Some Antiepileptic Drugs During Pregnancy Can Have A Negative Impact On The Development Of The CNS Of The Teens – Part 2 of 3
The teens exposed to more than one anti-epileptic drug in the womb were less likely to get a final grade than those in the general population, said Forsberg. Not receiving a end grade generally means not attending general school because of mental deficits.
While teens exposed to only one anti-seizure medication did not show the same risk, they were less likely to pass with excellence. This may be the follow-up of the influence of the anti-epileptic drug during fetal life, but it may also be the effect of factors related to epilepsy, such as genetic factors, social factors and the effect of the mother’s seizures, said Forsberg. “Therefore, these details should be interpreted with caution”.
Anti-epileptic medications besides valproic acid include phenytoin (such as Dilantin and Phenytek) and carbamazepine (such as Tegretol and Carbatrol). The study noted that compared to other anti-epileptic drugs, valproic acid during pregnancy seems to have a stronger antipathetic influence on cognitive skills. However, Forsberg said that this study could not draw specific conclusions about valproic acid, since very few of the children well-thought-out were exposed to it.
There’s also evidence that taking multiple anti-epileptic drugs can cause more harm than taking just one. That’s why the American Academy of Neurology recommends taking just one during pregnancy, if possible, and trying medications other than valproic acid.