Amphotericin B And Flucytosine For Antifungal Therapy – Part 2 of 3
But, Hirsch notorious that this infection is unusual to see in the United States. That’s definitely not the case in the rest of the world. There are about 1 million cases of cryptococcal meningitis worldwide each year, and 625000 deaths associated with those infections, according to review background information. Meningitis is an infection of the meninges, the protective membranes that cover the brain and the spinal cord.
Meningitis can be caused by bacteria, viruses and fungi, according to the US Centers for Disease Control and Prevention. Cryptococcal meningitis is caused by the fungus Cryptococcus. There are 30 strains of Cryptococcus, and one that often causes affliction is Cryptococcus neoformans. “Most of us have been exposed to Cryptococcus neoformans.
It is ubiquitous in the environment, associated with trees, bird guano and soil. Infection is contemplating to occur from the inhalation of spores”. People can be infected for years without knowing it, according to Day. But, if someone who’s infected has weakened immunity, the infection can then shrink to wreak havoc. Common ways people become immune-suppressed are through an HIV infection, taking immune-suppressing medications for organ transplantation, or taking immune-system altering medications for dyed in the wool inflammatory diseases.