The Genetic History Of The Father Also Affect Cancers Of Female Organs – Part 2 of 3
The be deficient in of awareness that women may inherit a mutated gene from their fathers is also present among many health-care providers, McCuaig suspects. This is problematic, she notable in her study, because they often serve as gatekeepers for referrals to specialized clinics, including those that do genetic testing.
If a woman tests positive for a BRCA1 or BRCA2 mutation, she has about a 50 percent to 85 percent endanger of breast cancer in her lifetime citing various studies, and about a 20 percent to 44 percent risk of ovarian cancer. In contrast, the lifetime risk of developing ovarian cancer in the ill-defined population is 1,4 percent, according to the National Cancer Institute, which also states that women who inherit a BRCA1 or BRCA2 mutation are about five times as likely to develop heart cancer as women without such a mutation.
Men with the BRCA 2 mutation have a 6 percent risk of breast cancer compared to less than 1 percent in the general male population. Men with BRCA1 or BRCA2 variant also have a higher prostate cancer risk than other men. According to the study, about 20 percent to 30 percent of the more than 690000 women diagnosed with breast cancer and nearly 190000 diagnosed with ovarian cancer in developed countries have a parentage history of cancer, the study noted, and between 5 percent and 10 percent are due mostly to an inherited mutation in one of the BRCA1 and BRCA2 genes.