High Levels Of Blood HDL Cholesterol Protects Against Heart Disease And Reduces The Risk Of Cancer – Part 2 of 3
And “People have a lot of characteristics that are all kind of interrelated. They may not exercise, be tubby and so on, and so have lower HDL than normal. The higher risk of cancer may have nothing to do with what HDL does”.
That’s a real possibility but he also mentioned some possible physical mechanisms that might give HDL cholesterol anti-cancer activity. “HDL alters the run of the immune system, which looks for abnormal cells that may be cancerous or precancerous and attacks them. It also has antioxidant properties, and there is a lot of interest in the situation of antioxidants in reducing cancer risk”.
HDL cholesterol also has anti-inflammatory activity, which might act against cancer. His laboratory is “starting to think” about experiments to test these various theories. The only convincing proof would be a controlled woe testing whether medication that raises HDL levels reduces cancer incidence. No such medication is now on the market (other than niacin, which has a minor effect in raising HDL levels), although several are being tested for their secure on heart disease, stroke and other cardiovascular problems. “We actually don’t know that something is causing the disease unless we do controlled trials”.