Stem Cells From A New Source For The Treatment Of The Heart – Part 2 of 3
The journal report describes laboratory apply in which stem cells obtained from amniotic membranes were transformed into heart cells, 33 percent of which beat spontaneously and which improved rat heart function by more than 34 percent when injected two weeks after a goodness attack. The injected cells decreased the area of heart damage by 13 percent to 18 percent and survived for more than four weeks in the rats without the use of drugs to brawl immune rejection. The amniotic cells are much easier to convert into heart cells than stem cells from other sources, such as bone marrow or fat.
They probably can be converted just as easily to cells of extraordinary organs. The immunological neutrality of the cells is “quite fascinating or mysterious”. One theory is that the amniotic sac bars the immune systems of the mother-to-be and her fetus from attacking each other by not producing the HLA proteins that specify foreign tissue.
A number of studies using stem cells to repair heart damage are ongoing in the United States, said Dr Douglas W Losordo, leader of the Feinberg Cardiovascular Research Institute. Most studies have tried to use cells from the patient’s own tissue, such as bone marrow.
So “There have been lots of animal studies and preliminary studies in patients penetrating at repairing damage in heart attacks. There have been many discussions about whether some cells are better than others, and what sources of cells are available”.