Promising Transplants Of Blood Vessels For Dialysis Patients – Part 1 of 3
Promising Transplants Of Blood Vessels For Dialysis Patients. In premature research, blood vessels originating from a donor’s skin cells and grown in a laboratory have been successfully implanted in three dialysis patients. These engineered grafts have functioned well for about 8 months, power researchers reporting Monday at a special online conference sponsored by the American Heart Association. The three patients – all of whom lived in Poland and were on dialysis for end-stage kidney cancer – received the new vessels to allow better access for dialysis.
But the expectation is that these types of bioengineered, “off-the-shelf” tissues can someday be used as replacement arteries throughout the body, including heart bypass. “The grafts available now perform quite poorly,” said superintend researcher Todd N McAllister, co-founder and chief executive officer of Cytograft Tissue Engineering Inc, the Novato, California-based maker of the grafts and the funder of the study. Currently, these types of vessels are typically made of pseudo material or they are grafts of the patient’s own veins.
In either case the rate of failure and the need for redoing the procedures remains high. In the new study, benefactress skin cells were used to grow the blood vessels. The vessels were made from sheets of cultured skin cells, rolled around a temporary support structure in the lab.