Promising Transplants Of Blood Vessels For Dialysis Patients – Part 2 of 3
Upon implantation the vessels typically even about a foot long and a fifth of an inch in diameter. After implantation, the vessels were used as “shunts” between arteries and veins in the arm to gave the patient access to life-saving dialysis. “To stage all the grafts are patent functioning well. Perhaps most interestingly, we have seen no clinical manifestations of an immune response”.
In fact, over eight months after implantation, none of the patients show any signs of rejecting the graft. The grafts have also been able to manage the high pressures and frequent needle punctures needed to deliver dialysis, the researchers found.
In earlier work, McAllister’s group showed that vessels grown using a patient’s own veneer cells reduced the rate of complications typically seen with shunts by more than two-fold over 3 years. However, the advantage of these new vessels, grown from donor cells, is that it won’t obtain six months to grow the tissue.